Bhargavacharitham Moonnam Khandam movie revolves around a notorious underworld Don of Kochi called 'Current Bhargavan' (Mammootty), who is always accompanied by funny looking goons (Johny and Mohan Jose). The present problem of the Don is that he has lost confidence and can't pick up a gun or be violent anymore. He accidentally hears the oration of world renowned psychiatrist Dr Shantharam (Sreenivasan), who boasts that he can even treat Bin Laden to come back to activities of peace. The Don then forcefully acquires the help of the psychiatrist..